This lecture note explains the basic
concepts, facts, and principles of cell biology at the molecular level and to
develop basic skills to read current cell biology literature and to develop
basic understanding of the integration of engineering with biology.
Author(s): Ge Yang, Department of Biomedical
Engineering, Carnegie Mellon University
This note covers the following
topics: Protein Structure and Function, The Flow of Information: DNA to Protein,
Ribosome, mRNA, and tRNA direct the Synthesis of Proteins, Gene Regulation, DNA
Packing and Organization, Cell Cycle and Division, Cell Signaling, Cell
Junctions, Cell Adhesion and ECM, Nervous System.
This note covers the
following topics: Precellular evolution, Oparin and Haldane hypothesis,
Precursors to purines, Origin of polymers, Conservation of Group 1 introns, RNA
as polymerase, RNA as nuclease and ligase, RNA genome, Genetic code and
David Fitch, Department of Biology, New York University
This note explains the following topics: Epigenetic mechanisms controlling mesodermal specification, Imaging chromatin in
embryonic stem cells, Epigenetic silencing during early lineage commitment, The
chromatin signature of pluripotent cells, Stem cells, cancer, and epigenetics.