Structural Biology Reading

Biochemistry and Structural Biology

This note covers the following topics: Structural Biology and Amino acids, History of Macromolecular Crystallography, Amino acid Chirality, Non-covalent interactions and Ramachandran Map, Secondary structures; Introduction to Protein , Alpha-domain proteins I: Coiled coils and four-helix bundle, ROP protein design, Alpha-domain proteins II: Large alpha-helical domain and globin fold, Alpha or Beta-domain proteins, Beta-domain proteins.

Author(s): Dr. R. Sankararamakrishnan

NA Pages

Workshop In Computational Structural Biology

This note explores the concepts and algorithms that enable computational modeling of biological molecules, in both theory and practice. Topics covered includes: The basics of protein structure, Rosetta and structural modeling, Optimization techniques, Analysis of protein structures and assessment of model quality, Full atom refinement and side chain modeling, Hands-on: Side chain modeling, Homology modelin, Protein-protein docking.

Author(s): Prof. Ora Furman

NA Pages

Mathematical Techniques In Structural Biology

These are notes about using mathematics to study the molecular structure of molecules, especially long organic molecules like DNA and proteins. Topics covered includes: Molecular Genetics: DNA, Proteins, Frames and moving frames, Orthogonal transformations and Rotations, Torsion angles and pdb files, X-ray Crystallography, Lattices, and Fourier Series, Nuclear Magnetic Resonance and distance geometry, Protein Folding.

Author(s): J. R. Quine

86 Pages

Diffraction Techniques in Structural Biology

This book combines a general overview of diffraction methods with a step-by-step description of the process of a single-crystal X-ray structure determination experiment, from chemical synthesis or expression to phasing and refinement, analysis and quality control . Topics covered includes: Major techniques in structural biology, X-ray fiber diffraction, Electron diffraction, Electron microscopy, Neutron diffraction, Nuclear magnetic resonance spectroscopy, Single crystal X-ray crystallography.

Author(s): Martin Egli

NA Pages

Protein Structure

The aim of this book is that a non expert can gain some appreciation for the intricacies involved, and in the current state of affairs. The expert meanwhile, can gain a deeper understanding of the topic.

Author(s): Eshel Faraggi

396 Pages

Structural biology Protein Crystallography

This note covers the following topics: Principles of protein structure, Hemoglobin, Platelet adhesion to collagen and Blood clotting.

Author(s): Utrecht University

NA Pages