This note
explains the following topics: Structure Of Hemoglobin, Structure Of Globin,
Structure Of Heme, Structure And Function Of Myoglobin, Biomedical Importance Of
Myoglobin, Transport Of O2 By Hb, Conformational Changes Accompany Oxygenation
Of Hb, Mechanism Of Bohr Effect, Chloride Shift, Biosynthesis Of Heme, Acute
Intermittent Porphyria , Congenital Erythropoietic Porphyria, Porphyria Cutanea
Tarda.
Author(s): SRM Institute of Science and Technology
The
book has been divided into three sections. The first section includes chapters
describing the immunological and coagulation-assisting functions of red blood
cells and methods to measure their life span. The second section discusses the
role of platelets in inflammatory processes. The third section reviews
functional dose of RBC transfusions and transfusion practice in various clinical
settings.
The
primary objective of this book is to provide the specialists involved in the
clinical management and experimental research in hematological diseases with
comprehensive and concise information on some important theoretical and
practical developments in the biology, clinical assessment, and treatment of
patients, as well as on some molecular and pathogenetic mechanisms and the
respective translation into novel therapies.
Author(s): Margarita Guenova and Gueorgui Balatzenko
The book, Inherited Hemoglobin
Disorders, describes the genetic defects of hemoglobins, disease complications,
and therapeutic strategies. This book has two distinct sections. The first theme
includes seven chapters devoted to the types of hemoglobinopathies, mutation
spectrum, diagnostic methods, and disease complications, and the second theme
includes three chapters focusing on various treatment strategies. Major topics
covered includes: Hemoglobinopathy Approach Diagnosis and Treatment Policy,
Thalassemia, Sickle Cell Disease, Acute Splenic Sequestration Crisis, Sickle
Cell Disease.
The lecture note is intended for use by
laboratory technologist both during their training and in their work places.
There are study questions at the end of each chapter for the reader to evaluate his
understanding of the contents. In addition, important terms are defined in the
glossary section at the end of the text.
Author(s): Yared Alemu,
Alemayehu Atomsa and Zewdneh Sahlemariam