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Principles of Drug Development

This book presents principles underlying preclinical and clinical development of new therapeutic drugs and procedures.Also describes and evaluates specific examples, and discusses legal and ethical regulations that apply to drug development.

Author(s): Johns Hopkins University

NA Pages

This note cover Pharmacodynamics, Pharmacokinetics, Pharmacokinetic Modelling, Exponential Functions, Variability in Drug Response, Drug Interaction, Adverse Drug Reactions, Drug Additives, Isomerism, Respiratory Drugs, Vaso Active Drug, Vasodilators, Diuretic, Anti-Arrhythmic Drugs, Neuromuscular Blocking Agents, Anticholinesterase Agents, CNS Neurotransmitters, Malignant Hyperthermia, Histamine Agents, Anti Microbials, Vasopressin, Analgesia, Fluid Replacement and Miscellaneous Toxicology.

Author(s): Adam Hollingworth

434 Pages

Pharmacology by EPHTI

Pharmacology is the study of interaction of drugs with living organisms. It also includes history, source, physicochemical properties, dosage forms, methods of administration, absorption, distribution mechanism of action, biotransformation, excretion, clinical uses and adverse effects of drugs. This PDF covers the following topics related to Pharmacology : General pharmacology, Drugs acting on autonomic nervous system, Cardiovascular-renal drugs, Autacoids and their antagonists, Drugs Action on the Respiratory System, Drugs used in Gastrointestinal Diseases, Drugs used to treat the diseases of blood, inflammation and gout, Drugs acting in the central nervous system, Endocrine Drugs, Chemotherapeutic Agents, Toxicology, Prescription writing and rational use of drugs.

Author(s): Teferra Abula, Srinivasa A.Rao, Amare Mengistu, Solomomon Worku, Eshetu Legesse, Musie Aberra, Dawit, University of Gondar

211 Pages

Basic Concepts in Pharmacology What You Need to Know for Each Drug Class

Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class is not a conventional review book for pharmacology. It is a book to help you organize your attack on the hundreds of drugs covered in pharmacology classes today. Our survey for the first edition of this book made it clear that it is the number of drugs in a particular class that students find overwhelming. This fear causes many students to lose focus on the most important part of pharmacology�the concepts.

Author(s): Janet L Stringer

NA Pages

Antimicrobial drugs

This note covers the following topics: Penicillin, Antimicrobial effect, Antimicrobial drugs, Selective Toxicity, Chemotherapeutic index, The Ideal Drug, Side effects of chemotherapy, Antibiotic Mechanisms of Action, Beta-lactam antibiotics, Beta-lactamase inhibitors, Glycopeptides, Mechanism of vancomycin resistance, Antibiotics Inhibiting Protein Synthesis, Makrolides and lyncosamides, Chloramphenicol, Tetracycline, Antibiotics Acting As Antimetabolites, Quinolones.

Author(s): Dora Szabo

83 Pages

Anticoagulant Drugs

This book gives an overview of all the known anticoagulants that can be useful for studying different aspects of the haemostatic system or as a starting point for new drug development. It is also a valuable tool for clinicians providing a description of the mode of action and management of therapy for anticoagulant drugs used in daily clinical practice in different clinical settings, including direct oral anticoagulants dabigatran, rivaroxaban, edoxaban and apixaban .

Author(s): Mojca Boxic-Mijovski

NA Pages

Pharmacology and Nutritional Intervention in the Treatment of Disease

Pharmacology and Nutritional Intervention in the Treatment of Disease is a book dealing with an important research field that has worldwide significance. Its aim is to strengthen the research base of this field of investigation as it yields knowledge that has important implications for biomedicine, public health and biotechnology. The basic purpose of this book was to promote interaction and discussion of problems of mutual interests among people in related fields everywhere.

Author(s): Faik Atroshi

426 Pages

Principles and Practice of Drug Development

This note serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process.

Author(s): Prof. Charles Cooney, Stan Finkelstein, MD, Dr. G. K. Raju and Prof. Anthony Sinskey

NA Pages

Recent Advances in Novel Drug Carrier Systems

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. Topics covered includes: Hot-Melt Extrusion, Development and Investigation of Dry Powder Inhalers for Cystic Fibrosis, The Role of Carrier in Dry Powder Inhaler, Nanotechnology in Drug Delivery, Lipid Nanoparticulate Drug Delivery Systems, Niosomes as Carrier in Dermal Drug Delivery, Magnetic Nanoparticles, Targeted Nanoparticles for Cancer Therapy, Amphiphilic Cyclodextrins, Synthesis, Utilities and Application of Molecular Modeling in Their Design, Nanoparticles Toxicity and Their Routes of Exposures.

Author(s): Ali Demir Sezer

512 Pages

Respiratory Drug Guidelines

It is hoped that these guidelines will be used by all health care workers in their daily care of patients suffering from respiratory diseases. Topics covered includes: Drugs used in respiratory diseases, Inhalation drug delivery devices, Pulmonary function testing, Asthma, Chronic obstructive pulmonary disease, Cough, Upper respiratory tract Infections, Lower respiratory tract Infections, Suppurative lung disease, Interstitial lung disease, Pre- and post-operative Respiratory assessment.

Author(s): Ministry of Health, Government of Fiji Islands

111 Pages

Drug Discovery and Development From Molecules to Medicine

In the fields of medicine, drug discovery is the process by which new candidate medications are discovered. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.

Author(s): Omboon Vallisuta and Suleiman Olimat

328 Pages

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Principles of Drug Development

Principles of Drug Development

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