This note covers the
following topics: Molecular Biology, Molecular Biology Information - DNA,
Protein Sequence, Macromolecular Structure and Protein Structure Details, Gene
Expression Datasets, New Paradigm for Scientific Computing, General Types of
Informatics in Bioinformatics, Genome Sequence, Protein Sequence, Major
Application: Designing Drugs, Finding Homologues, Genome Characterization.
This note
covers the following topics: what is bioinformatics, Path to the bioinformatics, Scope of computational biology, The Central Dogma of
Molecular Biology, Genomics, Proteomics, Killer application, Cells, Signaling
Pathways Control gene activity, DNA the code of life and genetic information
chromosomes.
This note explains the
following topics: Modern approaches in Bioanalysis and Bioassays, Spectroscopic
techniques: UV-Visible spectroscopy, Fluorescence spectroscopy, IR spectroscopy,
CD spectroscopy, and Mass spectroscopy, Light Microscopy; Fluorescence
microscopy, Atomic force microscope, Electron microscope, Scanning electron
microscopy, Transmission Electron microsope, Application of microscope in
analyzing biological samples.
This book is intended to serve both
as a textbook for short bioinformatics courses and as a base for a self teaching
endeavor. It is divided in two parts: A. Bioinformatics Techniques and B. Case
Studies. Each chapter of the first part addresses a specific problem in
bioinformatics and consists of a theoretical part and of a detailed tutorial
with practical applications of that theory using software freely available on
the Internet.
This note explains the basic bioinformatics concepts via a closed lab
exercise and a programming project. Also discusses the implementation of these
activities and some of the results/lessons we learned.