This
note covers the following topics: Basic Quantum Mechanics, UV absorption,
Fluorescence, Circular Dichroism, IR/Raman, Intro Proteins, NMR, Solid State NMR,
Single molecule, Protein-DNA Interactions, Calorimitry, X-ray, Electron
Microscopy, Mass Spectrometry.
Author(s): University of Pittsburgh School of Medicine
This
note covers the following topics: Basic Quantum Mechanics, UV absorption,
Fluorescence, Circular Dichroism, IR/Raman, Intro Proteins, NMR, Solid State NMR,
Single molecule, Protein-DNA Interactions, Calorimitry, X-ray, Electron
Microscopy, Mass Spectrometry.
Author(s): University of Pittsburgh School of Medicine
This note aims
to provide the knowledge of the basic protein molecular architecture and then to
connect it to the basic cellular processes like enzymatic activity, transport
and membrane functions.
These are notes about
using mathematics to study the molecular structure of molecules, especially long
organic molecules like DNA and proteins. Topics covered includes: Molecular
Genetics: DNA, Proteins, Frames and moving frames, Orthogonal transformations
and Rotations, Torsion angles and pdb files, X-ray Crystallography, Lattices,
and Fourier Series, Nuclear Magnetic Resonance and distance geometry, Protein
Folding.
This book combines a
general overview of diffraction methods with a step-by-step description of the
process of a single-crystal X-ray structure determination experiment, from
chemical synthesis or expression to phasing and refinement, analysis and quality
control . Topics covered includes: Major techniques in structural biology, X-ray
fiber diffraction, Electron diffraction, Electron microscopy, Neutron
diffraction, Nuclear magnetic resonance spectroscopy, Single crystal X-ray
crystallography.
This note explains the following topics: Taxonomy : Primary and Secondary
Structure, Motifs and Supersecondary Structure, Tertiary Structure and Fold
Types, Forces that Determine Protein Structure, Mechanisms of Protein Folding,
Multiscale Modeling of Electrostatics.