This
note covers the following topics: functional groups, introduction and review,
ionic substitution SN2, nomenclature, conformations of acyclic molecules,
stereochemistry, introduction to aromaticity, addition to carbon- carbon pi
bonds, electrophilic aromatic substitution, conformations of cyclic molecules,
carbohydrates, radicals, infrared spectroscopy, carbonyl chemistry- reactions
and mechanisms, hnmr spectroscopy, enolates enols and enamines, C-NMR,2D-NMR and
MRI, organic chemistry of pharmaceuticals, solving spectroscopy problems , drug
development discovery to market, xray diffraction, noncovalent molecular
forces.
It focuses on synthetic organic chemistry, major topics in the
course, which include organometallic reagents, oxidation/reduction reactions,
complex synthesis. Covers synthesis and reactions of nonbenzenoid aromatic
compounds: tropone and tropolone, polycyclic aromatic compounds. This book
introduces students to the disconnection approach in synthetic strategy, and
protecting groups were discussed in great detail. It will be very useful for
postgraduate students in advanced organic synthesis, who would like to learn how
complex organic molecules are made.
It is
an advanced-level book that is focused on synthesis: particularly on strategies
for stereoselective synthesis. Methods for the stereocontrolled synthesis of
acyclic compounds that are essential to be built with specific three-dimensional
configurations are included. The book focuses a lot on the latest techniques and
strategies in building complex organic structures, discussing much about
reaction mechanisms and problems with stereoselectivity in synthetic pathways.
This is the definitive resource for graduate students and researchers in organic
synthesis and for those who want to be better equipped with a deeper
understanding of synthetic methodologies.