Introduction to Micorarrays and Concepts of Molecular Biology
Introduction to Micorarrays and Concepts of Molecular Biology
Introduction to Micorarrays and Concepts of Molecular Biology
The
topics in this presentation are : Overview of Molecular and Cellular Biology,
Part I: Molecular Biology Review, Life, Cell types, Prokaryotic Cell,
Eukaryotes, Nucleic Acids, DNA, RNA, Central Dogma, Gene Transcription or DNA
Transcription, Translation, Ribosome, Chromosomes, Chromatin Structure, Gene
Coding and Replication, Mitosis, Proteins, Polymerase Chain Reaction,
Introduction to Microarrays, Microarray Data Analysis, For What Do We Use
Microarray Data?, Statistical Methods Can Help, Preprocessing Microarray Data,
etc.
Author(s): M. Saleet Jafri,
Program in Bioinformatics and Computational Biology, George Mason University
This note covers basic concepts in molecular biology, Genes
structure and expression, Mutation, Bacterial and viral genetics, Recombination
and gene transfer mechanisms.
Molecular genetics, or molecular biology, is the study of the
biochemical mechanisms of inheritance. It is the study of the biochemical nature
of the genetic material and its control of phenotype. It is the study of the
connection between genotype and phenotype. The connection is a chemical one. The
chapters explained in this book are : The Cell, the Cell Cycle, Macromolecules,
Genetics, Chromosome Structure and Function, Linkage, Pedigree Analysis, Nucleic
Acid Structure and Function, Dna Damage and Repair, Gene Transfer in Bacteria,
Transcription and Translation, Control of Gene Expression, Recombinant Dna
Technology, Dna Sequencing, Molecular Techniques.
This is the third edition of
a book that was initiated with the annotation of the function of all the genes
in the most commonly studied baculovirus, AcMNPV. The second and third
editions involved the update of this information and its integration into
chapters covering the major processes central to the replication and pathology
of baculoviruses. Topics including taxonomy, the application of baculoviruses
as insecticides, the molecular basis for the remarkable ability of these
viruses to express genes at high levels, and the interrelationships of
baculovirus and transposable elements are also covered.
This book gives a
comprehensive overview of recent advances in Retrovirology, as well as general
concepts of molecular biology of retroviral infections, immunopathology,
diagnosis, and prevention, to current clinical recommendations in management
of retroviruses, including endogenous retroviruses, highlighting the ongoing
issues, recent advances, with future directions in diagnostic approaches and
therapeutic strategies.