This note covers the following topics: Penicillin,
Antimicrobial effect, Antimicrobial drugs, Selective Toxicity, Chemotherapeutic
index, The Ideal Drug, Side effects of chemotherapy, Antibiotic Mechanisms of
Action, Beta-lactam antibiotics, Beta-lactamase inhibitors, Glycopeptides,
Mechanism of vancomycin resistance, Antibiotics Inhibiting Protein Synthesis,
Makrolides and lyncosamides, Chloramphenicol, Tetracycline, Antibiotics Acting
As Antimetabolites, Quinolones.
The guideline on Drug misuse sets out clear, evidence-based recommendations
for healthcare staff on how to work with people who misuse opioids to
significantly improve their treatment and care, and to deliver detoxification
safely and effectively.
Author(s): National Collaborating Centre for Mental Health
(UK)
This book contains
information on drugs and other chemicals to which breastfeeding mothers may be
exposed. It includes information on the levels of such substances in breast milk
and infant blood, and the possible adverse effects in the nursing infant.
Suggested therapeutic alternatives to those drugs are provided, where
appropriate.
This book gives an overview of all
the known anticoagulants that can be useful for studying different aspects of
the haemostatic system or as a starting point for new drug development. It is
also a valuable tool for clinicians providing a description of the mode of
action and management of therapy for anticoagulant drugs used in daily clinical
practice in different clinical settings, including direct oral anticoagulants
dabigatran, rivaroxaban, edoxaban and apixaban .
This note explains the
following topics: Principles of Pharmacology, Drug Absorption and Distribution,
Drug Elimination and Multiple Dosing, Clinical Pharmacokinetics, Drug
Metabolism, Pharmacogenomics, Drug Toxicity, Pharmacodynamics, Drugs Discovery
and Clinical Trials.
This note serves as a
description and critical assessment of the major issues and stages of developing
a pharmaceutical or biopharmaceutical. Topics covered include drug discovery,
preclinical development, clinical investigation, manufacturing and regulatory
issues considered for small and large molecules, and economic and financial
considerations of the drug development process.
Author(s): Prof. Charles Cooney, Stan
Finkelstein, MD, Dr. G. K. Raju and Prof. Anthony Sinskey
It is
hoped that these guidelines will be used by all health care workers in their
daily care of patients suffering from respiratory diseases. Topics covered
includes: Drugs used in respiratory diseases, Inhalation drug delivery
devices, Pulmonary function testing, Asthma, Chronic obstructive pulmonary
disease, Cough, Upper respiratory tract Infections, Lower respiratory tract
Infections, Suppurative lung disease, Interstitial lung disease, Pre- and
post-operative Respiratory assessment.
Author(s): Ministry of Health, Government of Fiji Islands
Pharmacology comprises some broad conceptions and
generalizations, and some detailed conclusions, of such great and practical importance that every
student and practitioner of medicine should be absolutely familiar with them. It
comprises also a large mass of minute details, idiich would constitute too great a tax on human memory, but which can not
safely be neglected. It is the ambition of this book to present both types of
information without confusion.
In the fields of medicine, drug discovery is the
process by which new candidate medications are discovered. This book
demonstrates that various expertise are essential for drug discovery including
synthetic or natural drugs, clinical pharmacology, receptor identification, drug
metabolism, pharmacodynamic and pharmacokinetic research. The following 5
sections cover diverse chapter topics in drug discovery: Natural Products as
Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery;
Receptors Involvement in Drug Discovery; Management and Development of Drugs
against Infectious Diseases; Advanced Methodology.
This note provides the details about drugs and over-the-counter
medicines. This includes side effects, dosage, and special precautions. Also
contains the details about dietary supplements and herbal remedies to learn about their
effectiveness, usual dosage, and drug interactions.
Natural products are a constant source of potentially active
compounds for the treatment of various disorders.Plant derived secondary
metabolites have been used by humans to treat acute infections, health disorders
and chronic illness for tens of thousands of years. Only during the last 100
years have natural products been largely replaced by synthetic drugs.Books on
drug discovery will play vital role in the new era of disease treatment using
natural products.