A Bioinformatics Study of Human Transcriptional Regulation

Foundations of Bioinformatics and Systems Biology

The contents in this site includes the following topics : The complete course is comprised of three modules covering Foundations of Bioinformatics, Statistics in Bioinformatics, Systems Biology. These modules holds the following contents : Introduction to bioinformatics, Sequence Alignment and Database Searching, Structural Bioinformatics, Genome Informatics: High Throughput Sequencing Applications and Analytical Methods, Approaches to statistical estimation and testing, Statistical estimation and hypothesis testing, Analyses involving associations, Pearson correlation, t-test, and log odds ratios, Linear regression, Regression models, Introduction to graphical methods for multivariate data analysis, Clustering and principal component analysis, Introduction to systems biology, Epigenome data mining to understand disease predisposition, Computational clinical decision support systems, Application of systems biology to translational medicine.

Author(s): University of Michigan

NA Pages

A Bioinformatics Study of Human Transcriptional Regulation

This PDF thesis A Bioinformatics Study of Human Transcriptional Regulation covers the following topics related to Bioinformatics : Biological background, DNA and chromosomes, Transcription, Transcriptional regulation, Medical aspects of transcriptional regulation, High-throughput technologies, DNA microarrays, Massively parallel sequencing, Biological knowledge sources, Annotations, Experimental data, Aims, Methods, Computational methods, Statistics Randomization, Local search, Analysis of high-throughput data, Experiment design, Expression analysis, ChIP-chip data analysis, ChIP-seq data analysis, Data storage and management, Results and discussion, Summary of results, Computational results, Biological results, Medical results, Additional results, Discussion.

Author(s): Adam Ameur

54 Pages

Bioinformatics Introduction by Mark Gerstein

This note covers the following topics: Molecular Biology, Molecular Biology Information - DNA, Protein Sequence, Macromolecular Structure and Protein Structure Details, Gene Expression Datasets, New Paradigm for Scientific Computing, General Types of Informatics in Bioinformatics, Genome Sequence, Protein Sequence, Major Application: Designing Drugs, Finding Homologues, Genome Characterization.

Author(s): Mark Gerstein

NA Pages

Introduction to Bioinformatics Lecture

This note explains the following topics: What is bioinformatics, Molecular biology primer, Biological words, Sequence assembly, Sequence alignment, Fast sequence alignment using FASTA and BLAST, Genome rearrangements, Motif finding, Phylogenetic trees and Gene expression analysis.

Author(s): Esa Pitkanen

431 Pages

Bioanalytical Techniques and Bioinformatics

This note explains the following topics: Modern approaches in Bioanalysis and Bioassays, Spectroscopic techniques: UV-Visible spectroscopy, Fluorescence spectroscopy, IR spectroscopy, CD spectroscopy, and Mass spectroscopy, Light Microscopy; Fluorescence microscopy, Atomic force microscope, Electron microscope, Scanning electron microscopy, Transmission Electron microsope, Application of microscope in analyzing biological samples.

Author(s): NPTEL

NA Pages

Bioinformatics and Proteomics

This note provides a hands-on approach to students in the topics of bioinformatics and proteomics. Topics covered includes: sequence analysis, microarray expression analysis, Bayesian methods, control theory, scale-free networks, and biotechnology applications.

Author(s): Prof. Gil Alterovitz, Prof. Manolis Kellis and Prof. Marco Ramoni

NA Pages