Human Papillomaviruses

Antivirals Virology

The contents of this lecture presentation include : Vaccines can prevent viral disease, Why are there so few antiviral drugs?, Antiviral history, Blind screening, Antiviral discovery today, The path of drug discovery, Mechanism-based screens, Cell-based screen, Antiviral screening, High throughput screening, Dangers of drug resistance, Mechanisms of drug resistance, Acyclovir mechanism of action, Improving acyclovir, Acyclovir-resistant HSV, Symmetrel, Influenza virus NA inhibitors, WIN compounds, Inhibitors of picornavirus uncoating, New HCV drugs, HCV new drug pipeline, Azido-deoxythymidine, AZT, Non-nucleoside RT inhibitors, IN inhibitors, Maraviroc: CCR5 inhibitor, Combination therapy, Mathematics of drug resistance, ART saves lives, Pre-exposure prophylaxis.

Author(s): Prof. Vincent Racaniello, Columbia University

61 Pages