The first Section
of this book provides readers with background and several methodologies for
understanding genetic disorders. Genetic defects, diagnoses and treatments of
the respective unifactorial and multifactorial genetic disorders are reviewed in
the second and third Sections.
The word genetics, coined by William Bateson, is derived
from the Latin word genesis, which means birth. Genetics is the study of
heredity and variation. Heredity refers to the transmission of genetic
information, more precisely genes, from parents to offspring. This PDF
Principles of Genetics and Cytogenetics covers the following topics related to
Genetics : Inrtoduction, Earlier Concepts of Heredity, Cytology, Chromosome
Morphology, Molecular Structure of Chromosome, Special Types of Chromosomes,
Cell Division, Sexual Reproduction, Mendelian Genetics, Gene Action, Principles
of Dominance, Lethal Genes, Epistasis / Gene Interaction, Multiple Alleles,
Qualitative and Quantitative Characters, Polygenic Inheritance, Linkage,
Crossing Over, Genetic and Physical Map, Sex Determination, Sex Determination in
Humanbeings, Mutation, Chromosomal Aberrations, the Structure of Dna, Dna
Replication, Rna as Genetic Material, the Genetic Code, Central Dogma of
Molecular Biology, Transcription and Translation, Regulation of Gene Expression,
Fine Structure of Genes, etc.
Author(s): T. Sabesan, K. Saravanan, S. Suganthi,
This note covers the
following topics: quantitative versus qualitative genetics, Hardy-Weinberg law
for gene frequency stability in large populations, Relationship and inbreeding,
Estimation of breeding values, Inbreeding, crossing and bred structure,
Chromosomes and chromosome aberrations, Genetics on hair and coat colour in
mammals, Estimating- and biotechnology and disease resistance.
The objective of this note is have a
greater awareness and appreciation of classical and molecular genetics with
emphasis on genetic material and its formation, transmission, function and
organization. Topics covered includes: historical perspective of genetics,
inheritance patterns and the chromosomal basis of heredity, sex chromosomes in
sex determination and sexual dimorphism, cells reproduce through DNA and nucleic
acids, DNA transcribes into RNA that ultimately translates into protein,
prokaryotic and eukaryotic genes, genetic basis of cancer and how it relates to
the cell cycle.
This lecture note discusses the principles
of genetics with application to the study of biological function at the level of
molecules, cells, and multicellular organisms, including humans. Topics covered
includes: structure and function of genes, chromosomes and genomes, biological
variation resulting from recombination, mutation, and selection, population
genetics, use of genetic methods to analyze protein function, gene regulation
and inherited disease.
Author(s): Prof. Chris Kaiser, Prof. Gerald Fink, Prof.
Leona Samson and Dr. Michelle Mischke
This book explains
the following topics: Mendelian analysis, The chromosomal theory of inheritance,
The chromosomal theory of inheritance, Brown Symposium, Chromosome Mutation,
Structure of DNA, Recombinant DNA techniques, Applications of recombinant DNA
techniques, Population genetics and Quantitative genetics.
Advanced Genetics provides an overview of
basic concepts and techniques in genetics and their use in answering fundamental
questions in biology. The lectures focus primarily on studies carried out in
yeast, C. elegans, Drosophila, mouse, and humans to illustrate the power of
genetics as an experimental tool.
University Department of Genetics
This book, Human
Genetic Diseases contains many diverse chapters, dealing with human genetic
diseases, methods to diagnose them, novel approaches to treat them and molecular
approaches and concepts to understand them. Although this book does not give a
comprehensive overview of human genetic diseases, and the sixteen book chapters
will be a valuable resource for researchers and students in different life and
This book aims to provide an overview on
some of the latest developments in several genetic diseases. It contains 14
chapters focused on various genetic disorders addressing epidemiology, etiology,
molecular basis and novel treatment options for these diseases.