The word genetics, coined by William Bateson, is derived
from the Latin word genesis, which means birth. Genetics is the study of
heredity and variation. Heredity refers to the transmission of genetic
information, more precisely genes, from parents to offspring. This PDF
Principles of Genetics and Cytogenetics covers the following topics related to
Genetics : Inrtoduction, Earlier Concepts of Heredity, Cytology, Chromosome
Morphology, Molecular Structure of Chromosome, Special Types of Chromosomes,
Cell Division, Sexual Reproduction, Mendelian Genetics, Gene Action, Principles
of Dominance, Lethal Genes, Epistasis / Gene Interaction, Multiple Alleles,
Qualitative and Quantitative Characters, Polygenic Inheritance, Linkage,
Crossing Over, Genetic and Physical Map, Sex Determination, Sex Determination in
Humanbeings, Mutation, Chromosomal Aberrations, the Structure of Dna, Dna
Replication, Rna as Genetic Material, the Genetic Code, Central Dogma of
Molecular Biology, Transcription and Translation, Regulation of Gene Expression,
Fine Structure of Genes, etc.
Author(s): T. Sabesan, K. Saravanan, S. Suganthi,
This note covers the
following topics: quantitative versus qualitative genetics, Hardy-Weinberg law
for gene frequency stability in large populations, Relationship and inbreeding,
Estimation of breeding values, Inbreeding, crossing and bred structure,
Chromosomes and chromosome aberrations, Genetics on hair and coat colour in
mammals, Estimating- and biotechnology and disease resistance.
The objective of this note is have a
greater awareness and appreciation of classical and molecular genetics with
emphasis on genetic material and its formation, transmission, function and
organization. Topics covered includes: historical perspective of genetics,
inheritance patterns and the chromosomal basis of heredity, sex chromosomes in
sex determination and sexual dimorphism, cells reproduce through DNA and nucleic
acids, DNA transcribes into RNA that ultimately translates into protein,
prokaryotic and eukaryotic genes, genetic basis of cancer and how it relates to
the cell cycle.
This lecture note discusses the principles
of genetics with application to the study of biological function at the level of
molecules, cells, and multicellular organisms, including humans. Topics covered
includes: structure and function of genes, chromosomes and genomes, biological
variation resulting from recombination, mutation, and selection, population
genetics, use of genetic methods to analyze protein function, gene regulation
and inherited disease.
Author(s): Prof. Chris Kaiser, Prof. Gerald Fink, Prof.
Leona Samson and Dr. Michelle Mischke
This lecture note
covers the following topics: The genetic structure of populations, Genetic
transmission in populations, The genetics of natural selection, Genetic drift,
Quantitative genetics, Molecular evolution, Phylogeography.
Advanced Genetics provides an overview of
basic concepts and techniques in genetics and their use in answering fundamental
questions in biology. The lectures focus primarily on studies carried out in
yeast, C. elegans, Drosophila, mouse, and humans to illustrate the power of
genetics as an experimental tool.
University Department of Genetics
Medical genetics involves the
application of genetic principles in the practice of medicine. Medical genetics
encompasses diagnosis and treatment of genetic diseases, study of inheritance of
diseases in families, mapping of disease genes to their chromosome locations,
study of the molecular genetics and pathogenesis of inherited disorders,
provision of genetic counseling for families, and recently, investigations of
methods for gene therapy. Topics covered includes: Mendelian Genetics, Non-Mendelian
Genetics, Clinical Cytogenetics, Dysmorphology, Genetic Counseling, Prenatal
Diagnosis, Clinical DNA Diagnosis, Cancer Genetics, Problem Solving in Genetics,
Legal and Ethical Issues in Human Genetics.
The first Section
of this book provides readers with background and several methodologies for
understanding genetic disorders. Genetic defects, diagnoses and treatments of
the respective unifactorial and multifactorial genetic disorders are reviewed in
the second and third Sections.
From the National Center for Biotechnology Information,
Genes and Disease is an online collection of articles that discuss genes and the
diseases that they cause. These genetic disorders are organized by the parts of
the body that they affect.
This note covers the following topics: Children
resemble their parents, Genes come in pairs, Some genes are dominant, Genetic
inheritance, Genes are real things, cells arise from pre-existing cells, Sex
cells, Specialized chromosomes determine gender, Chromosomes carry genes,
Evolution begins with the inheritance of gene variation, Mendelian laws apply to
human beings, Genetic organization and control.