Pharmacology is
the study of interaction of drugs with living organisms. It also includes
history, source, physicochemical properties, dosage forms, methods of
administration, absorption, distribution mechanism of action, biotransformation,
excretion, clinical uses and adverse effects of drugs. This PDF covers the
following topics related to Pharmacology : General pharmacology, Drugs acting on
autonomic nervous system, Cardiovascular-renal drugs, Autacoids and their
antagonists, Drugs Action on the Respiratory System, Drugs used in
Gastrointestinal Diseases, Drugs used to treat the diseases of blood,
inflammation and gout, Drugs acting in the central nervous system, Endocrine
Drugs, Chemotherapeutic Agents, Toxicology, Prescription writing and rational
use of drugs.
Author(s): Teferra Abula, Srinivasa A.Rao, Amare Mengistu, Solomomon
Worku, Eshetu Legesse, Musie Aberra, Dawit, University of Gondar
Pharmacology is
the study of interaction of drugs with living organisms. It also includes
history, source, physicochemical properties, dosage forms, methods of
administration, absorption, distribution mechanism of action, biotransformation,
excretion, clinical uses and adverse effects of drugs. This PDF covers the
following topics related to Pharmacology : General pharmacology, Drugs acting on
autonomic nervous system, Cardiovascular-renal drugs, Autacoids and their
antagonists, Drugs Action on the Respiratory System, Drugs used in
Gastrointestinal Diseases, Drugs used to treat the diseases of blood,
inflammation and gout, Drugs acting in the central nervous system, Endocrine
Drugs, Chemotherapeutic Agents, Toxicology, Prescription writing and rational
use of drugs.
Author(s): Teferra Abula, Srinivasa A.Rao, Amare Mengistu, Solomomon
Worku, Eshetu Legesse, Musie Aberra, Dawit, University of Gondar
This note covers the following topics: Penicillin,
Antimicrobial effect, Antimicrobial drugs, Selective Toxicity, Chemotherapeutic
index, The Ideal Drug, Side effects of chemotherapy, Antibiotic Mechanisms of
Action, Beta-lactam antibiotics, Beta-lactamase inhibitors, Glycopeptides,
Mechanism of vancomycin resistance, Antibiotics Inhibiting Protein Synthesis,
Makrolides and lyncosamides, Chloramphenicol, Tetracycline, Antibiotics Acting
As Antimetabolites, Quinolones.
This book gives an overview of all
the known anticoagulants that can be useful for studying different aspects of
the haemostatic system or as a starting point for new drug development. It is
also a valuable tool for clinicians providing a description of the mode of
action and management of therapy for anticoagulant drugs used in daily clinical
practice in different clinical settings, including direct oral anticoagulants
dabigatran, rivaroxaban, edoxaban and apixaban .
This book presents some in-depth
reviews of selected topics in drug metabolism. Topics covered includes: Oral
Absorption, Intestinal Metabolism and Human Oral Bioavailability,
Pharmacogenetics and Metabolism, Altered Drug Metabolism and Transport in
Pathophysiological Conditions, Anticancer Drug Metabolism: Chemotherapy
Resistance and New Therapeutic Approaches, Transcription Factors Potentially
Involved in Regulation of Cytochrome P450 Gene Expression, Electrochemical
Methods for the In Vitro Assessment of Drug Metabolism, Pharmacogenomic
Technology for Personalized Medicine.
This book presents Pharmacogenetic examples from a broad spectrum of
different drugs, for different diseases, which are representative of different
stages of evaluation or application. It has been designed so as to serve both
the unfamiliar reader through explanations of basic Pharmacogenetic concepts,
the clinician with presentation of the latest developments and international
guidelines, and the research scientist with examples of Pharmacogenetic
applications, discussions on the limitations and an outlook on the new
scientific trends in this field.
This note explains the
following topics: Principles of Pharmacology, Drug Absorption and Distribution,
Drug Elimination and Multiple Dosing, Clinical Pharmacokinetics, Drug
Metabolism, Pharmacogenomics, Drug Toxicity, Pharmacodynamics, Drugs Discovery
and Clinical Trials.
The authors of this book look from different
angles to hypertension, sharing their new knowledge and experience in the
direction of deep understanding and more clarification of the disease providing
an invaluable resource not only for clinicians, but also for all medical
sciences students and health providers.
This book considers the basic principles of biopharmaceutics and
pharmacokinetics. It also illustrates clinical pharmacokinetic applications,
such as recirculatory models, common antimalarial drugs, and clinical
pharmacokinetic principles in critically ill patients, which are essential for
medical professionals.
The object of the
course note is to teach students an approach to the study of pharmacologic
agents. It is not intended to be a review of the pharmacopoeia. The focus is on
the basic principles of biophysics, biochemistry and physiology, as related to
the mechanisms of drug action, biodistribution and metabolism.
Author(s): Dr.
Carl Rosow, Dr. David Standaert and Prof. Gary Strichartz
This book covers the
following topics: Basic Principles, Autonomic Pharmacology, Anesthesia, Pain
medications, Antimicrobial agents, Cardiovascular Pharmacology.