This is an interactive
multimedia version of the book Concepts in Biochemistry. The dynamic
instructional resources featured are intended to supplement and extended the
critical concepts presented in the Boyers textbook.
This note covers the following
topics: Amino acids and proteins, Properties of proteins in solutions, Blood
proteins, Nucleic acids, Carbohydrates, Phospholipids, steroids and fat-soluble
vitamins, Enzymes, Digestive tract enzymes, The enzymatic reaction maximum
velocity and the Michaelis constant, Enzymatic activity, Competitive and
non-competitive inhibition, Oxidative decarboxylation of pyruvate, Glutaminase,
Glycogen synthesis and degradation, Synthesis and degradation of starch,
Catalase, Protein nitrogen, amino acid transamination, Biochemical
This book contains an overview focusing on the
research area of proteins, enzymes, cellular mechanisms and chemical compounds
used in relevant approaches. The book deals with basic issues and some of the
recent developments in biochemistry. Topics covered includes: Protein
Flexibility and Coiled-Coil Propensity, Peptides and Peptidomimetics as Tools to
Probe Protein-Protein Interactions – Disruption of HIV-1 gp41 Fusion Core and
Fusion Inhibitor Design, Profilin, and Vascular Diseases, E. coli Alpha
Hemolysin and Properties, Human ER alpha and ER beta Splice Variants, GPCRs and G Protein
Activation, Carbonic Anhydrase and Heavy Metals, Enzymology of Bacterial Lysine
Biosynthesis, Glucose Metabolism and Cancer, Modulation of EAAC1, Mechanism of
Cargo Recognition During Selective Autophagy, Cholesterol.
contains precisely referenced chapters, emphasizing antibacterial agents with
clinical practicality and alternatives to synthetic antibacterial agents through
detailed reviews of diseases and their control using alternative approaches.
book covers the following topics: Acids, Bases and Buffers, Physiological
Buffers and Amino Acids, Peptides, Proteins, Protein Structure & Function,
Protein Purification, Enzyme Kinetics, Enzyme Inhibition and Coenzymes,
Carbohydrates, Lipids and Membranes, Cellular Metabolism & the Chemistry of
Metabolism, Glycolysis, Pyruvated Dehydrogenase & the TCA Cycle, Lipid and Fat
This note explains the advanced treatment of the biochemical
mechanisms that underlie biological processes. Topics include are macromolecular
machines for energy and force transduction, regulation of biosynthetic and
degradative pathways, Cholesterol biosynthesis and the structure and function of
Author(s): Prof. Joanne Stubbe and Prof.
note explains the equilibrium properties of macroscopic and microscopic systems,
basic thermodynamics, chemical equilibrium of reactions in gas and solution
phase, and macromolecular interactions.
Moungi Bawendi, Prof. Kimberly Hamad-Schifferli and Prof. Linda G. Griffith
The course note provides students with a
research-inspired laboratory experience that introduces standard biochemical
techniques in the context of investigating a current and exciting research
topic, acquired resistance to the cancer drug Gleevec. Techniques include
protein expression, purification, and gel analysis, PCR, site-directed
mutagenesis, kinase activity assays, and protein structure viewing.