Foundations of Bioinformatics and Systems Biology

Bioinformatics by Nakaya Helder

This page covers the following topics related to Bioinformatics : Text Mining Gene Selection to Understand Pathological Phenotype Using Biological Big Data, Single-Cell RNA Sequencing Procedures and Data Analysis, Computational Methods for Detecting Large-Scale Structural Rearrangements in Chromosomes, Machine Learning Approaches for Biomarker Discovery Using Gene Expression Data, Bayesian Inference of Gene Expression, Comprehensive Evaluation of Error-Correction Methodologies for Genome Sequencing Data, Plant Transcriptome Assembly: Review and Benchmarking,WeMine Aligned Pattern Clustering System for Biosequence Pattern Analysis, Rational Design of Profile Hidden Markov Models for Viral Classification and Discovery, Pattern Discovery and Disentanglement for Aligned Pattern Cluster Analysis and Protein Binding Complexes Detection.

Author(s): Nakaya Helder I., PhD.

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Computational Biology Biostatistics

The topics of notes in this site are as follows : Introduction to Bioinformatics, Sequence Alignment, Probabilistic Sequence Models , Gene Expression Analysis, Protein Structure Prediction.

Author(s): Burr Settles

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Foundations of Bioinformatics and Systems Biology

The contents in this site includes the following topics : The complete course is comprised of three modules covering Foundations of Bioinformatics, Statistics in Bioinformatics, Systems Biology. These modules holds the following contents : Introduction to bioinformatics, Sequence Alignment and Database Searching, Structural Bioinformatics, Genome Informatics: High Throughput Sequencing Applications and Analytical Methods, Approaches to statistical estimation and testing, Statistical estimation and hypothesis testing, Analyses involving associations, Pearson correlation, t-test, and log odds ratios, Linear regression, Regression models, Introduction to graphical methods for multivariate data analysis, Clustering and principal component analysis, Introduction to systems biology, Epigenome data mining to understand disease predisposition, Computational clinical decision support systems, Application of systems biology to translational medicine.

Author(s): University of Michigan

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Bioinformatics Introduction by Mark Gerstein

This note covers the following topics: Molecular Biology, Molecular Biology Information - DNA, Protein Sequence, Macromolecular Structure and Protein Structure Details, Gene Expression Datasets, New Paradigm for Scientific Computing, General Types of Informatics in Bioinformatics, Genome Sequence, Protein Sequence, Major Application: Designing Drugs, Finding Homologues, Genome Characterization.

Author(s): Mark Gerstein

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Bioanalytical Techniques and Bioinformatics

This note explains the following topics: Modern approaches in Bioanalysis and Bioassays, Spectroscopic techniques: UV-Visible spectroscopy, Fluorescence spectroscopy, IR spectroscopy, CD spectroscopy, and Mass spectroscopy, Light Microscopy; Fluorescence microscopy, Atomic force microscope, Electron microscope, Scanning electron microscopy, Transmission Electron microsope, Application of microscope in analyzing biological samples.

Author(s): NPTEL

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Bioinformatics and Proteomics

This note provides a hands-on approach to students in the topics of bioinformatics and proteomics. Topics covered includes: sequence analysis, microarray expression analysis, Bayesian methods, control theory, scale-free networks, and biotechnology applications.

Author(s): Prof. Gil Alterovitz, Prof. Manolis Kellis and Prof. Marco Ramoni

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