This textbook is
intended for a sophomore-level, two-semester course in Organic Chemistry
targeted at Biology, Biochemistry, and Health Science majors. Topics covered
includes: Organic structure and bonding, Conformation and Stereochemistry,
Structure determination, Organic reactivity, Acid-base reactions, Nucleophilic
substitution reactions.
This
note covers the following topics:Derivatives Of Hydrocarbons, Alcohols, Phenols, Ethers And Epoxides ,
Derivatives Of Hydrocarbons, Aldehydes, Ketons, Carboxylic Acids, Functional
Derivatives Of Monocarboxylic Acids , Nitro Compounds, Organosulphur And Organo
Phosphorus, Organic Compounds Of Nitrogen, Amino Compounds , Organosulphur And
Organo Phosphorus Compound.
This note explains the following
topics: Fundamental stereochemical concepts, Synthetic strategy and principles
for stereoselective in particular enantioselective, chemical transformations,
Transition metal catalysis, Applications of frontier orbital theory,
Retrosynthetic analysisand Advanced organic synthesis.
In this note the
basics of enediyne class of natural and designed antitumor antibiotics, their
history of discovery, novel biological activity, and their medicinal application
will be focused. Also this note will describe the history of discovery of
enediyne class of natural products, their molecular architechture, mode of
biological action and the key chemistry behind their potent DNA cleaving
activity.
This note is designed to
provide a unified overview of fundamental organic chemistry for science majors. Students who successfully complete the reading of
this note acquire an integrated understanding of molecular architecture,
molecular transformations, reaction energetics and mechanisms, synthetic
strategy, and structure determination.
The primary guiding and unifying
principle of the book is the structural theory in its broadest sense. This one
theory underlies the whole of organic chemistry; its different aspects are
discussed in the various chapters.
This lecture note focuses on the methods used to
identify the structure of organic molecules, advanced principles of organic
stereochemistry, organic reaction mechanisms, and methods used for the synthesis
of organic compounds.
Author(s): Dr. Kimberly Berkowski
and Prof. Timothy F. Jamison