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An Introduction to Mass Spectrometry
This note gives a fairly accessible introduction to the principles and applications of mass spectrometry. It starts by outlining important topics, such as sample introduction, ionization techniques (electron and chemical ionization), and mass analyzers. It then discusses the different types of detectors and the vacuum systems required for successful analysis. It offers a tutorial overview of how mass spectrometry can be applied to the analysis of complex chemical systems, including an introduction to data systems and interpretation techniques. This note is perfect for newcomers in the analytical chemistry arena seeking to get a good grasp of the basics of mass spectrometry.
Author(s): Scott E. Van Bramer
38 Pages 
This resource from the Scripps Center for Metabolomics introduces the fundamental concepts of mass spectrometry (MS), so it is very good for beginners. It includes the most essential facts about MS that concern the principles of ionization, mass analyzers, and detectors, as well as information on the vacuum system required for MS analysis. The note gives foundational knowledge of how MS works: from the generation of ions from a sample to the separation process and on to detection. Suitable for practitioners who are just beginning a career in analytical chemistry or metabolomics, it provides an easily accessible introduction to the technology and applications in the analysis of complex molecular systems.
Author(s): Scripps Center for Metabolomics
NA Pages
Tandem Mass Spectrometry Molecular Characterization
This book serves as an introduction to tandem mass spectrometry (MS/MS) and its role in molecular characterization in chemical and biological research areas. It is tailored to professionals and students alike and assesses the application of MS/MS in studying complex molecules such as drugs, metabolites, carbohydrates, and proteins. The authors explain how tandem mass spectrometry can provide detailed structural information and insights into post-translational modifications. This resource is ideal for those looking to understand the powerful applications of MS/MS in molecular biology and chemistry, with emphasis on its versatility in biological and pharmaceutical sciences.
Author(s): Ana Varela Coelho and Catarina de Matos Ferraz Franco
204 Pages