Analytical Chemistry Agricultural Chemistry Applied Chemistry BioChemistry Crystal Chemistry ElectroChemistry Environmental Chemistry Acid Base Chemistry General Chemistry InOrganic Chemistry Kitchen Chemistry Laboratory Chemistry Materials Chemistry BioChemistry Medicinal Chemistry Astrochemistry Books Marine Chemistry Molecular Chemistry Nuclear Chemistry Organic Chemistry OrganoMetallic Chemistry Physical Chemistry Polymer Chemistry Practical Chemistry Quantum Chemistry SpectroMetry Spectroscopy SupraMolecular Chemistry Surface Analysis Theoretical Chemistry Computational Chemistry
Principles and Applications of Mass Spectrometry
This note presents an overview of mass spectrometry at an advanced level with specific emphasis on its utility in chemistry and biochemistry. Fundamental concepts include ionization, mass analyzers, and dissociation of ions, as well as more advanced topics like ion mobility and fragmentation. The qualitative and quantitative analysis using mass spectrometry and the practical applications in various fields are also considered. This note is designed for advanced students and professionals aiming to gain insights into the role of mass spectrometry as an analytical tool, both in theory and practice.
Author(s): Derek J. Wilson
37 Pages 
This advanced PDF explores mass spectrometry from the computational and algorithmic perspective. Peptide de novo sequencing, database searching, and comparing mass spectra using significance testing, such as p-values and E-values, are discussed in this note. It also covers isotope distributions and fragmentation patterns to shed light on the mathematical aspects behind its analysis of mass spectrometry data. It reaches more complex dimensions and discusses issues like glycan sequencing, machine learning, and decomposition of the isotope pattern. Finally, the note is an invaluable resource for anyone interested in mass spectrometry and computational methods, providing a foundation for yet more complicated applications in bioinformatics and structural biology.
Author(s): Sebastian Bocker
253 Pages
Mass Spectrometry Basics for Young Students An Interactive Laboratory Tour
This guide is designed to introduce young students aged between 6 and 14 to the field of mass spectrometry in a highly interactive and hands-on laboratory experience. It describes the basic principles of the technique in a way that is fun and accessible for children. It can be adapted in modules to accomodate various age groups, providing an educational approach to an introduction to the field of mass spectrometry. This resource sparks young minds toward exploration of scientific concepts, especially in chemistry and biology, and encourages curiosity about the world of molecular analysis.
Author(s): American Society for Mass Spectrometry
36 Pages