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Principles and Applications of Mass Spectrometry
This note presents an overview of mass spectrometry at an advanced level with specific emphasis on its utility in chemistry and biochemistry. Fundamental concepts include ionization, mass analyzers, and dissociation of ions, as well as more advanced topics like ion mobility and fragmentation. The qualitative and quantitative analysis using mass spectrometry and the practical applications in various fields are also considered. This note is designed for advanced students and professionals aiming to gain insights into the role of mass spectrometry as an analytical tool, both in theory and practice.
Author(s): Derek J. Wilson
37 Pages 
Mass Spectrometry by Prof. Peter B. OConnor
Prof. Peter B. O'Connor's note on mass spectrometry. It deals with the interpretation of mass spectra; it would be particularly useful for any persons undertaking the analysis of unknown samples. It starts by dealing with a range of techniques, among them being electron impact ionization, MS/MS fragmentation, and ion sources. In addition, the note goes into practical implementations of mass spectrometry in real-world applications such as protein complex analysis, hydrogen and deuterium exchange, and imaging mass spectrometry. The course takes the student through advanced topics like 2D FTICR mass spectrometry, an expansive full view of modern mass spectrometric methods and their practical use in research and industry.
Author(s): Prof. Peter B. OConnor
NA Pages
Tandem Mass Spectrometry Molecular Characterization
This book serves as an introduction to tandem mass spectrometry (MS/MS) and its role in molecular characterization in chemical and biological research areas. It is tailored to professionals and students alike and assesses the application of MS/MS in studying complex molecules such as drugs, metabolites, carbohydrates, and proteins. The authors explain how tandem mass spectrometry can provide detailed structural information and insights into post-translational modifications. This resource is ideal for those looking to understand the powerful applications of MS/MS in molecular biology and chemistry, with emphasis on its versatility in biological and pharmaceutical sciences.
Author(s): Ana Varela Coelho and Catarina de Matos Ferraz Franco
204 Pages