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Tandem Mass Spectrometry Molecular Characterization
This book serves as an introduction to tandem mass spectrometry (MS/MS) and its role in molecular characterization in chemical and biological research areas. It is tailored to professionals and students alike and assesses the application of MS/MS in studying complex molecules such as drugs, metabolites, carbohydrates, and proteins. The authors explain how tandem mass spectrometry can provide detailed structural information and insights into post-translational modifications. This resource is ideal for those looking to understand the powerful applications of MS/MS in molecular biology and chemistry, with emphasis on its versatility in biological and pharmaceutical sciences.
Author(s): Ana Varela Coelho and Catarina de Matos Ferraz Franco
204 Pages 
This is a comprehensive note on X-ray spectroscopy techniques, aimed at detailing their applications in different fields, with an emphasis on the special applications in nanoparticles and molecular mechanisms. It begins with the introduction of XRF processes and techniques followed by high-resolution X-ray spectroscopy using compound semiconductor detectors and digital pulse processing systems. It also includes analytic applications of X-ray techniques, including dispersive X-ray spectroscopy as well as quantification in X-ray fluorescence spectrometry. In addition, it approaches specialized uses such as time-resolved X-ray absorption spectroscopy in the study of metalloproteins and the application of soft X-rays in astrochemistry. The note concludes discussing nanoscale chemical analysis that highlights energy dispersive X-ray spectroscopy (EDX) and transmission electron microscopy (TEM) with relevance to the characterization of interfaces and materials on the nanoscale.
Author(s): Shatendra K. Sharma
290 Pages
An Introduction to Mass Spectrometry
This note gives a fairly accessible introduction to the principles and applications of mass spectrometry. It starts by outlining important topics, such as sample introduction, ionization techniques (electron and chemical ionization), and mass analyzers. It then discusses the different types of detectors and the vacuum systems required for successful analysis. It offers a tutorial overview of how mass spectrometry can be applied to the analysis of complex chemical systems, including an introduction to data systems and interpretation techniques. This note is perfect for newcomers in the analytical chemistry arena seeking to get a good grasp of the basics of mass spectrometry.
Author(s): Scott E. Van Bramer
38 Pages