This resource from the Scripps Center for Metabolomics
introduces the fundamental concepts of mass spectrometry (MS), so it is very
good for beginners. It includes the most essential facts about MS that concern
the principles of ionization, mass analyzers, and detectors, as well as
information on the vacuum system required for MS analysis. The note gives
foundational knowledge of how MS works: from the generation of ions from a
sample to the separation process and on to detection. Suitable for practitioners
who are just beginning a career in analytical chemistry or metabolomics, it
provides an easily accessible introduction to the technology and applications in
the analysis of complex molecular systems.
This resource from the Scripps Center for Metabolomics
introduces the fundamental concepts of mass spectrometry (MS), so it is very
good for beginners. It includes the most essential facts about MS that concern
the principles of ionization, mass analyzers, and detectors, as well as
information on the vacuum system required for MS analysis. The note gives
foundational knowledge of how MS works: from the generation of ions from a
sample to the separation process and on to detection. Suitable for practitioners
who are just beginning a career in analytical chemistry or metabolomics, it
provides an easily accessible introduction to the technology and applications in
the analysis of complex molecular systems.
This note gives
a fairly accessible introduction to the principles and applications of mass
spectrometry. It starts by outlining important topics, such as sample
introduction, ionization techniques (electron and chemical ionization), and mass
analyzers. It then discusses the different types of detectors and the vacuum
systems required for successful analysis. It offers a tutorial overview of how
mass spectrometry can be applied to the analysis of complex chemical systems,
including an introduction to data systems and interpretation techniques. This
note is perfect for newcomers in the analytical chemistry arena seeking to get a
good grasp of the basics of mass spectrometry.