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This resource from the Scripps Center for Metabolomics introduces the fundamental concepts of mass spectrometry (MS), so it is very good for beginners. It includes the most essential facts about MS that concern the principles of ionization, mass analyzers, and detectors, as well as information on the vacuum system required for MS analysis. The note gives foundational knowledge of how MS works: from the generation of ions from a sample to the separation process and on to detection. Suitable for practitioners who are just beginning a career in analytical chemistry or metabolomics, it provides an easily accessible introduction to the technology and applications in the analysis of complex molecular systems.
Author(s): Scripps Center for Metabolomics
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Mass Spectrometry by Prof. Peter B. OConnor
Prof. Peter B. O'Connor's note on mass spectrometry. It deals with the interpretation of mass spectra; it would be particularly useful for any persons undertaking the analysis of unknown samples. It starts by dealing with a range of techniques, among them being electron impact ionization, MS/MS fragmentation, and ion sources. In addition, the note goes into practical implementations of mass spectrometry in real-world applications such as protein complex analysis, hydrogen and deuterium exchange, and imaging mass spectrometry. The course takes the student through advanced topics like 2D FTICR mass spectrometry, an expansive full view of modern mass spectrometric methods and their practical use in research and industry.
Author(s): Prof. Peter B. OConnor
NA Pages
