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Mass Spectrometry IMM
In mass spectrometry, one generates ions from a sample to be analyzed. These ions are then separated and quantitatively detected. The units covered in this notes are as follows : Introduction, Charge Location and Fragmentation, Ion Separation, Ionization and Desorption, Biomolecules, Literature, Sources.
Author(s): Peter M. van Galen and Martin C. Feiters, Department of Organic Chemistry, Molecular Chemistry Cluster, Institute for Molecules and Materials, Faculty of Science, Radboud University, Nijmegen
65 Pages 
This advanced PDF explores mass spectrometry from the computational and algorithmic perspective. Peptide de novo sequencing, database searching, and comparing mass spectra using significance testing, such as p-values and E-values, are discussed in this note. It also covers isotope distributions and fragmentation patterns to shed light on the mathematical aspects behind its analysis of mass spectrometry data. It reaches more complex dimensions and discusses issues like glycan sequencing, machine learning, and decomposition of the isotope pattern. Finally, the note is an invaluable resource for anyone interested in mass spectrometry and computational methods, providing a foundation for yet more complicated applications in bioinformatics and structural biology.
Author(s): Sebastian Bocker
253 Pages
Mass Spectrometry Basics for Young Students An Interactive Laboratory Tour
This guide is designed to introduce young students aged between 6 and 14 to the field of mass spectrometry in a highly interactive and hands-on laboratory experience. It describes the basic principles of the technique in a way that is fun and accessible for children. It can be adapted in modules to accomodate various age groups, providing an educational approach to an introduction to the field of mass spectrometry. This resource sparks young minds toward exploration of scientific concepts, especially in chemistry and biology, and encourages curiosity about the world of molecular analysis.
Author(s): American Society for Mass Spectrometry
36 Pages